Habitual exercise and arterial aging

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Habitual exercise and arterial aging.

Aging affects the function and structure of arteries and increases the risk of cardiovascular diseases (CVD). In healthy sedentary adults, aging is associated with increased stiffness (reduced compliance) of large elastic arteries; impaired vascular endothelial function, including reductions in endothelium-dependent dilation (EDD), release of tissue-type plasminogen activator (fibrinolytic capa...

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Aging, habitual exercise, and dynamic arterial compliance.

BACKGROUND A reduction in compliance of the large-sized cardiothoracic (central) arteries is an independent risk factor for the development of cardiovascular disease with advancing age. METHODS AND RESULTS We determined the role of habitual exercise on the age-related decrease in central arterial compliance by using both cross-sectional and interventional approaches. First, we studied 151 hea...

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Effect of aging and habitual aerobic exercise on endothelial function, arterial stiffness, and autonomic function in humans

Effect of aging and habitual aerobic exercise on endothelial function, arterial stiffness, and autonomic function in humans.

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Habitual exercise program protects murine intestinal, skeletal, and cardiac muscles against aging.

Aging and aerobic exercise are two conditions known to interfere with health and quality of life, most likely by inducing oxidative stress to the organism. We studied the effects of aging on the morphological and functional properties of skeletal, cardiac, and intestinal muscles and their corresponding oxidative status in C57BL/6 mice and investigated whether a lifelong moderate exercise progra...

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Arterial intima-media thickness: site-specific associations with HRT and habitual exercise.

We determined the site-specific relations of hormone replacement therapy (HRT) and habitual exercise status with intima-media thickness (IMT) in both elastic (carotid) and muscular (femoral) arteries in 77 healthy postmenopausal women: 43 women were sedentary (20 no-HRT and 23 HRT users) and 34 women were endurance trained (14 no-HRT and 20 HRT users). Femoral IMT was not different among the se...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2008

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.90553.2008